Astragalus membranaceus has the effects of tonifying qi, promoting yang, solidifying the surface, supporting the toxic muscles, and reducing the swelling of water. In recent years, great progress has been made in the study of its pharmacological effects.
1, enhance immune function
Astragalus can enhance the phagocytic function of the reticuloendothelial system, significantly increase the number of white blood cells and multinucleated white blood cells, and increase the percentage of macrophage phagocytosis and phagocytic index, and promote the humoral immunity and cellular immunity. After taking normal people, plasma IgM and IgE increased significantly, and the whole grass effect was the best. Astragalus can promote the formation of serum hemolysin, improve the hemolysis ability of plaque forming cells, and have obvious carbon particle clearance and increase spleen weight. The above effects exist under normal physiological conditions and also have a significant effect when the immune function is low. Astragalus membranaceus not only enhances immune function, but also has a two-way regulation. The active ingredient F3 of Astragalus membranaceus has been shown to have complete recovery of lymphocyte function in cancer patients in vitro. It has been shown to completely reverse the immunosuppression caused by cyclophosphamide in animal model tests in vivo, suggesting that jaundice may be immunotherapy. It is a promising biological response modifier. Astragalus can increase the activity of natural killer cells (LAK) activated by lymphokine (interleukin-2).
2, the role of interferon
Astragalus has the ability to enhance the virus-induced interferon. Those who are susceptible to cold take jaundice during the cold season, which not only can significantly reduce the number of colds, but also make the cold symptoms milder and the disease course shorter.
3, enhance the body's tolerance to hypoxia and stress
Astragalus polysaccharide has obvious anti-fatigue effect, can significantly prolong the swimming time and increase the adrenaline weight of hydrocortisone-depleted mice, and has significant tolerance to various hypoxic models in mice, which can significantly reduce the whole body. Sexual oxygen consumption and increased tissue tolerance to hypoxia. Astragalus polysaccharide has obvious low temperature resistance, which can significantly prolong the anti-survival time of normal and deficient mice.
4, promote the body metabolism
Astragalus can enhance the physiological metabolism of cells, which may be accomplished by the regulation of intracellular cAMP and cGMP. Astragalus can also promote protein renewal in serum and liver, and promote protein metabolism, which may be another important aspect of Astragalus.
5, improve heart function
Astragalus membranaceus has a strengthening contraction effect on the normal heart. For the heart that is depleted due to poisoning or fatigue, the cardiotonic effect is more pronounced, which can increase the amplitude of the heart contraction and increase the blood volume. 100% Astragalus injection can strengthen and accelerate the contraction of isolated hearts. Astragalus can improve the left ventricular function of patients with viral myocarditis, and there is a certain anti-arrhythmia effect, which may be caused by prolonging the effective refractory period.
6, antihypertensive effect
Subcutaneous or intravenous injection of anthrax decoction, water infusion, alcohol infusion into anesthetized animals (dogs, cats, rabbits) can reduce blood pressure, and the effect is rapid, and the duration is short. The antihypertensive effect is the result of direct expansion of the peripheral blood vessels. Injecting Astragalus injection into the canine vascular, vertebral artery, superior mesenteric artery, cerebrovascular, intestinal vascular and other visceral blood vessels, the vascular resistance index can be decreased, but the renal artery is injected into the renal artery, and the renal vascular resistance index is increased, suggesting that the jaundice is on the kidney. The role of blood vessels is different from that of other parts of the blood vessels.
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