Use of acetaminophen: a systemic fungicide , mainly used to control powdery mildew in crops such as apples, greenhouse roses and strawberries.
The physicochemical properties of acetaminophen: the vapor pressure at 20 ° C is 0.5 * 106 mmHg. It has a solubility of 22 mg/l in water at room temperature, is soluble in most organic solvents, and is insoluble in alkanes. Kow5000 (PH7). Stability: Easy to hydrolyze in dilute acid, unstable storage over 37 °C for a long time. The half-life in soil is 35-90 days (pH 5.1-7.3). The industrial drug mp is about 40-45 ° C.
Acetyl phenol toxicity: The oral acute LD50 of female rats, mice, rabbits and male guinea pigs is about 4000 mg/kg. No clinical symptoms were observed after transdermal treatment of rats at a dose of 500 mg/kg daily for 10 days. Slightly irritating to rabbit eyes. The rats were fed with a drug containing 1000 ppm of the drug for 90 days, and no disease-causing effect was found. The no-effect dose for feeding the dog for 90 days was 15 mg/kg.
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