The whole genome sequence analysis of the probiotic Lactobacillus, L. casei Zhang, conducted by the Ministry of Education Key Laboratory of "Milk Biotechnology and Engineering" of Inner Mongolia Agricultural University lasted for 15 months and was completed in recent days. This is the first complete sequencing of lactic acid bacteria in China that has been independently completed and has completely independent intellectual property rights, which indicates that the research on lactic acid bacteria genomics in China has reached the international level.
L.casei Zhang is a probiotic with complete independent intellectual property rights that has been separated and screened by Inner Mongolia Agricultural University for more than 6 years, and has been systematically researched and developed. This project has received the National 863 Program, the National Natural Science Foundation of China, and the Key Projects for Scientific Research of the Ministry of Education. Funded by various projects such as the Virtual Dairy Research Institute of Inner Mongolia Autonomous Region.
At present, the international research on probiotics has entered the genetic era, especially the use of proteomics, genomics, metabolomics techniques and methods, can effectively and accurately identify the functional characteristics and functional genes of probiotics.
The completion of L.casei Zhang's complete genome sequence lays a foundation for the study of the probiotic mechanism of this strain and the development and application of related products, which greatly improves the scientific and efficiency of research and development. The completion of the project has made the research of probiotic lactic acid bacteria in China enter a new stage of development. This new technology will drive the development of probiotic lactic acid bacteria research and market industrialization in China.
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